Nora Ephron has died at the age of 71 after a battle with leukemia. The screenwriter, journalist and director rose to fame after writing hugely successful films, specialising in rom-coms including When Harry Met Sally and Sleepless in Seattle.

Tom Hanks and wife Rita Wilson released a statement saying: “Nora Ephron was a journalist/artist who knew what was important to know; how things really worked, what was worthwhile, who was fascinating and why. At a dinner table and on a film set she lifted us all with wisdom and wit, mixed with love for us and love for life. Rita and I are so very sad to lose our friend who brought so much joy to all who were lucky enough to know her.”

When Harry Met Sally star Billy Crystal said: “When Harry Met Sally …” in his remembrance of the multi-hyphenate talent. “I am very sad to learn of Nora’s passing. She was a brilliant writer and humorist. Being her Harry to Meg’s Sally will always have a special place in my heart. I was very lucky to get to say her words.”

Nicole Kidman said” “She was so smart, warm and funny. I am so grateful that she was my friend and we had the opportunity to work together. My thoughts and love are with her family at this time. I will never forget the dinners, games and laughter we all shared,”

Ephron married three times. One of her ex-husbands is Carl Bernstein. Her last husband was the basis of her motto at the end of her life: “Secret to life, marry an Italian.” Nicholas Pileggi wrote the screenplays to Goodfellas and Casino. They were married for 20 years.

She is survived by the two sons she had with Carl Bernstein.